Drug interactions
Amlodipine-olmesartan + Atenolol
Severity: Moderate
Amlodipine-olmesartan and Atenolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atenolol, amlodipine and olmesartan all lower blood pressure, and this combination is frequently used deliberately but may cause excess hypotension or bradycardia. Beta blockers can also modestly raise potassium, adding to the effect of olmesartan.
What this interaction means in plain words
Amlodipine-olmesartan and Atenolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan belongs to Cardiovascular; Atenolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects through beta blockade, calcium channel blockade and angiotensin receptor blockade; beta blockade slightly impairs cellular potassium uptake.
What to do
Monitor blood pressure, heart rate and serum potassium, particularly during dose changes. Reduce doses if symptomatic hypotension or bradycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Atenolol?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Atenolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atenolol, amlodipine and olmesartan all lower blood pressure, and this combination is frequently used deliberately but may cause excess hypotension or bradycardia. Beta blockers can also modestly raise potassium, adding to the effect of olmesartan.
How serious is the interaction between Amlodipine-olmesartan and Atenolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium, particularly during dose changes. Reduce doses if symptomatic hypotension or bradycardia occurs.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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