Drug interactions
Amlodipine-olmesartan + Betaxolol
Severity: Moderate
Amlodipine-olmesartan and Betaxolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol adds to the blood pressure lowering effect of amlodipine and olmesartan and may cause bradycardia or excessive hypotension. Beta blockers can also modestly raise serum potassium alongside the angiotensin receptor blocker.
What this interaction means in plain words
Amlodipine-olmesartan and Betaxolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amlodipine-olmesartan belongs to Cardiovascular; Betaxolol belongs to Cardiovascular.
Why it happens
Additive antihypertensive pharmacodynamic effects; beta blockade slightly impairs cellular potassium uptake.
What to do
Monitor blood pressure, heart rate and serum potassium when starting or adjusting therapy. Reduce doses if symptomatic hypotension or bradycardia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Betaxolol?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Betaxolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Betaxolol adds to the blood pressure lowering effect of amlodipine and olmesartan and may cause bradycardia or excessive hypotension. Beta blockers can also modestly raise serum potassium alongside the angiotensin receptor blocker.
How serious is the interaction between Amlodipine-olmesartan and Betaxolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium when starting or adjusting therapy. Reduce doses if symptomatic hypotension or bradycardia develops.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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