Drug interactions
Amlodipine-olmesartan + Celiprolol
Severity: Moderate
Amlodipine-olmesartan and Celiprolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Celiprolol is a beta-blocker with vasodilating properties, and combining it with amlodipine and olmesartan gives additive blood pressure reduction. Hypotension, dizziness and bradycardia may occur. The combination is often used intentionally but needs titration.
What this interaction means in plain words
Amlodipine-olmesartan and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic antihypertensive effects through beta-blockade, vasodilation, calcium channel blockade and angiotensin receptor blockade.
What to do
Monitor blood pressure and heart rate during initiation and dose changes, and reduce doses if symptomatic hypotension or bradycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Celiprolol?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Celiprolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Celiprolol is a beta-blocker with vasodilating properties, and combining it with amlodipine and olmesartan gives additive blood pressure reduction. Hypotension, dizziness and bradycardia may occur. The combination is often used intentionally but needs titration.
How serious is the interaction between Amlodipine-olmesartan and Celiprolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during initiation and dose changes, and reduce doses if symptomatic hypotension or bradycardia occurs.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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