Drug interactions
Amlodipine-olmesartan + Magnesium supplement
Severity: Minor
Amlodipine-olmesartan and Magnesium supplement: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Magnesium has mild calcium-antagonist and vasodilating properties, so it may add to the blood pressure lowering of amlodipine. Rarely, excessive hypotension or neuromuscular effects have been reported when calcium channel blockers are given with parenteral magnesium. Oral supplements at usual doses are seldom problematic.
What this interaction means in plain words
Amlodipine-olmesartan and Magnesium supplement have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive vasodilation and calcium channel antagonism, mainly with parenteral magnesium.
What to do
Monitor blood pressure when high-dose or intravenous magnesium is given with amlodipine. No adjustment is usually needed for oral supplements at usual doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Magnesium supplement?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Magnesium supplement have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Magnesium has mild calcium-antagonist and vasodilating properties, so it may add to the blood pressure lowering of amlodipine. Rarely, excessive hypotension or neuromuscular effects have been reported when calcium channel blockers are given with parenteral magnesium. Oral supplements at usual doses are seldom problematic.
How serious is the interaction between Amlodipine-olmesartan and Magnesium supplement?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when high-dose or intravenous magnesium is given with amlodipine. No adjustment is usually needed for oral supplements at usual doses.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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