Drug interactions
Amlodipine-olmesartan + Metformin
Severity: Minor
Amlodipine-olmesartan and Metformin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Calcium channel blockers can slightly impair glucose tolerance in some patients, but amlodipine has little clinically meaningful effect on glycemic control with metformin. No dose change is usually needed.
What this interaction means in plain words
Amlodipine-olmesartan and Metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-olmesartan belongs to Cardiovascular; Metformin belongs to Endocrine.
Why it happens
Possible small reduction in insulin sensitivity or secretion by calcium channel blockers; effect is minimal for amlodipine.
What to do
Continue routine glucose monitoring; no adjustment is normally required.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Other interactions of Metformin
Frequently asked questions
Can I take Amlodipine-olmesartan with Metformin?
MediHelp rates the interaction as minor. Amlodipine-olmesartan and Metformin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Calcium channel blockers can slightly impair glucose tolerance in some patients, but amlodipine has little clinically meaningful effect on glycemic control with metformin. No dose change is usually needed.
How serious is the interaction between Amlodipine-olmesartan and Metformin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue routine glucose monitoring; no adjustment is normally required.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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