Drug interactions
Amlodipine-olmesartan + Pindolol
Severity: Moderate
Amlodipine-olmesartan and Pindolol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pindolol adds to the blood pressure lowering of amlodipine and olmesartan, and may cause bradycardia or hypotension. Beta-blockers can also slightly raise potassium.
What this interaction means in plain words
Amlodipine-olmesartan and Pindolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antihypertensive effects through beta-blockade, calcium channel blockade and angiotensin receptor blockade.
What to do
Monitor blood pressure and heart rate when the combination is started or doses change. Check potassium in patients with renal impairment.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Amlodipine-olmesartan
- Aliskiren + Amlodipine-olmesartan Contraindicated
- Amlodipine-olmesartan + Sparsentan Contraindicated
- Amifostine + Amlodipine-olmesartan Major
- Amiloride + Amlodipine-olmesartan Major
- Amlodipine-olmesartan + Benazepril Major
- Amlodipine-olmesartan + Captopril Major
Frequently asked questions
Can I take Amlodipine-olmesartan with Pindolol?
MediHelp rates the interaction as moderate. Amlodipine-olmesartan and Pindolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pindolol adds to the blood pressure lowering of amlodipine and olmesartan, and may cause bradycardia or hypotension. Beta-blockers can also slightly raise potassium.
How serious is the interaction between Amlodipine-olmesartan and Pindolol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when the combination is started or doses change. Check potassium in patients with renal impairment.
What other medicines interact with Amlodipine-olmesartan?
MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.
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