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Drug interactions

Amlodipine-olmesartan + Shepherd's purse

Severity: Minor

Amlodipine-olmesartan and Shepherd's purse: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Shepherd's purse has been reported to affect blood pressure, so it might interfere with the antihypertensive control provided by olmesartan and amlodipine. The evidence is theoretical.

What this interaction means in plain words

Amlodipine-olmesartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible pharmacodynamic effect on vascular tone; mechanism not established.

What to do

Advise against using the herb in patients with hypertension, and monitor blood pressure if used.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Amlodipine-olmesartan with Shepherd's purse?

MediHelp rates the interaction as minor. Amlodipine-olmesartan and Shepherd's purse have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Shepherd's purse has been reported to affect blood pressure, so it might interfere with the antihypertensive control provided by olmesartan and amlodipine. The evidence is theoretical.

How serious is the interaction between Amlodipine-olmesartan and Shepherd's purse?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against using the herb in patients with hypertension, and monitor blood pressure if used.

What other medicines interact with Amlodipine-olmesartan?

MediHelp also lists interactions of Amlodipine-olmesartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Amlodipine-olmesartan page.

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