Drug interactions
Amoxapine + Terbutaline
Severity: Moderate
Amoxapine and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Amoxapine may potentiate the cardiovascular effects of terbutaline, including tachycardia, hypertension, and arrhythmia. Systemic terbutaline carries a greater risk than inhaled use.
What this interaction means in plain words
Amoxapine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic and cardiac effects due to norepinephrine reuptake inhibition.
What to do
Monitor heart rate, blood pressure, and ECG, especially with oral or parenteral terbutaline.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Frequently asked questions
Can I take Amoxapine with Terbutaline?
MediHelp rates the interaction as moderate. Amoxapine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amoxapine may potentiate the cardiovascular effects of terbutaline, including tachycardia, hypertension, and arrhythmia. Systemic terbutaline carries a greater risk than inhaled use.
How serious is the interaction between Amoxapine and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure, and ECG, especially with oral or parenteral terbutaline.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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