Drug interactions
Antithrombin alfa + Ginko biloba
Severity: Minor
Antithrombin alfa and Ginko biloba: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Antithrombin alfa potentiates heparin-type anticoagulation, and ginkgo has been reported to impair platelet function in some cases. The combination could theoretically increase bleeding, but supporting clinical evidence is weak.
What this interaction means in plain words
Antithrombin alfa and Ginko biloba have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive effect from ginkgolide inhibition of platelet-activating factor combined with enhanced thrombin inhibition; the mechanism is not firmly established.
What to do
Ask about herbal use and monitor for bleeding and coagulation parameters while antithrombin is given. Advise the patient to stop ginkgo if bleeding signs appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Frequently asked questions
Can I take Antithrombin alfa with Ginko biloba?
MediHelp rates the interaction as minor. Antithrombin alfa and Ginko biloba have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Antithrombin alfa potentiates heparin-type anticoagulation, and ginkgo has been reported to impair platelet function in some cases. The combination could theoretically increase bleeding, but supporting clinical evidence is weak.
How serious is the interaction between Antithrombin alfa and Ginko biloba?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use and monitor for bleeding and coagulation parameters while antithrombin is given. Advise the patient to stop ginkgo if bleeding signs appear.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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