Drug interactions
Antithrombin iii + Budesonide
Severity: Minor
Antithrombin iii and Budesonide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticosteroids have inconsistent effects on hemostasis and may alter clotting or affect vascular and mucosal integrity. Combined with antithrombin III concentrate, which enhances heparin-type anticoagulation, bleeding risk could theoretically rise. Clinical significance with budesonide is likely small.
What this interaction means in plain words
Antithrombin iii and Budesonide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive pharmacodynamic effects on hemostasis and mucosal integrity; the mechanism is not well established.
What to do
Monitor for bleeding and follow antithrombin activity and coagulation tests as already required during antithrombin therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Budesonide
Frequently asked questions
Can I take Antithrombin iii with Budesonide?
MediHelp rates the interaction as minor. Antithrombin iii and Budesonide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Corticosteroids have inconsistent effects on hemostasis and may alter clotting or affect vascular and mucosal integrity. Combined with antithrombin III concentrate, which enhances heparin-type anticoagulation, bleeding risk could theoretically rise. Clinical significance with budesonide is likely small.
How serious is the interaction between Antithrombin iii and Budesonide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and follow antithrombin activity and coagulation tests as already required during antithrombin therapy.
What other medicines interact with Budesonide?
MediHelp also lists interactions of Budesonide with, for example, Aldesleukin, Atazanavir, Bcg vaccine live. The full list is on the Budesonide page.
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