Drug interactions
Antithymocyte globulin equine + Measles mumps and rubella vaccine
Severity: Contraindicated
Antithymocyte globulin equine and Measles mumps and rubella vaccine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Equine antithymocyte globulin causes profound T-cell depletion, so live vaccine viruses may cause disseminated disease and the vaccine is unlikely to work. Live vaccines are avoided.
What this interaction means in plain words
Antithymocyte globulin equine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
Profound T-lymphocyte depletion impairs vaccine response and control of live attenuated viruses.
What to do
Do not give live vaccines during treatment or until immune recovery is confirmed, usually several months. Vaccinate beforehand when possible.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contraindicated
- Anakinra + Measles mumps and rubella vaccine Contraindicated
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicated
Frequently asked questions
Can I take Antithymocyte globulin equine with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Antithymocyte globulin equine and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Equine antithymocyte globulin causes profound T-cell depletion, so live vaccine viruses may cause disseminated disease and the vaccine is unlikely to work. Live vaccines are avoided.
How serious is the interaction between Antithymocyte globulin equine and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live vaccines during treatment or until immune recovery is confirmed, usually several months. Vaccinate beforehand when possible.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin rabbit. The full list is on the Measles mumps and rubella vaccine page.
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