Drug interactions
Arformoterol + Buprenorphine
Severity: Moderate
Arformoterol and Buprenorphine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have been linked to QT prolongation, and arformoterol can lower serum potassium. The combined risk is generally small but matters in patients with cardiac disease or other QT-prolonging drugs.
What this interaction means in plain words
Arformoterol and Buprenorphine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Buprenorphine belongs to Musculoskeletal.
Why it happens
Possible additive QT prolongation with beta-2 agonist-related hypokalemia.
What to do
Check ECG and electrolytes in patients with additional QT risk factors, and correct potassium and magnesium deficits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Buprenorphine
- Alvimopan + Buprenorphine Contraindicated
- Buprenorphine + Calcium / magnesium / potassium / sodium oxybates Contraindicated
- Buprenorphine + Olanzapine / samidorphan Contraindicated
- Buprenorphine + Phenelzine Contraindicated
- Buprenorphine + Pimozide Contraindicated
- Buprenorphine + Thioridazine Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Buprenorphine?
MediHelp rates the interaction as moderate. Arformoterol and Buprenorphine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have been linked to QT prolongation, and arformoterol can lower serum potassium. The combined risk is generally small but matters in patients with cardiac disease or other QT-prolonging drugs.
How serious is the interaction between Arformoterol and Buprenorphine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes in patients with additional QT risk factors, and correct potassium and magnesium deficits.
What other medicines interact with Buprenorphine?
MediHelp also lists interactions of Buprenorphine with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Olanzapine / samidorphan. The full list is on the Buprenorphine page.
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