Drug interactions
Arformoterol + Indapamide
Severity: Moderate
Arformoterol and Indapamide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol can lower serum potassium, and indapamide causes renal potassium loss. The combination may produce significant hypokalemia and ECG changes, particularly with high doses of the beta agonist.
What this interaction means in plain words
Arformoterol and Indapamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Indapamide belongs to Cardiovascular.
Why it happens
Additive hypokalemia from beta-2 mediated cellular uptake and diuretic kaliuresis.
What to do
Monitor serum potassium periodically and replace as required. Take extra care in patients with cardiac disease or hypoxia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indapamide
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Indapamide?
MediHelp rates the interaction as moderate. Arformoterol and Indapamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol can lower serum potassium, and indapamide causes renal potassium loss. The combination may produce significant hypokalemia and ECG changes, particularly with high doses of the beta agonist.
How serious is the interaction between Arformoterol and Indapamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium periodically and replace as required. Take extra care in patients with cardiac disease or hypoxia.
What other medicines interact with Indapamide?
MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.
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