Drug interactions
Arformoterol + Lithium
Severity: Moderate
Arformoterol and Lithium: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol can prolong QTc and lower potassium, and lithium has been associated with QT changes. Concurrent use may modestly raise arrhythmia risk, particularly in patients with cardiac disease.
What this interaction means in plain words
Arformoterol and Lithium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Lithium belongs to Central Nervous System.
Why it happens
Additive QTc prolongation, with beta2-agonist induced hypokalemia.
What to do
Monitor ECG and serum potassium in patients with cardiac disease or other QT risk factors. Use the lowest effective arformoterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Lithium
- Lithium + Thioridazine Contraindicated
- Lithium + Vandetanib Contraindicated
- Aceclofenac + Lithium Major
- Acemetacin + Lithium Major
- Amisulpride + Lithium Major
- Amlodipine-benazepril + Lithium Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Lithium?
MediHelp rates the interaction as moderate. Arformoterol and Lithium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol can prolong QTc and lower potassium, and lithium has been associated with QT changes. Concurrent use may modestly raise arrhythmia risk, particularly in patients with cardiac disease.
How serious is the interaction between Arformoterol and Lithium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac disease or other QT risk factors. Use the lowest effective arformoterol dose.
What other medicines interact with Lithium?
MediHelp also lists interactions of Lithium with, for example, Thioridazine, Vandetanib, Aceclofenac. The full list is on the Lithium page.
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