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Drug interactions

Arformoterol + Terbutaline

Severity: Moderate

Arformoterol and Terbutaline: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Combining terbutaline with the long-acting beta-agonist arformoterol duplicates beta-2 stimulation. This raises the chance of tachycardia, arrhythmia, tremor and hypokalemia, particularly in cardiac patients.

What this interaction means in plain words

Arformoterol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Arformoterol belongs to Respiratory; Terbutaline belongs to Respiratory.

Evidence level: Moderate

Why it happens

Additive beta-2 adrenergic agonism, including beta-mediated potassium shift into cells.

What to do

Avoid routine use of additional beta-agonists with arformoterol; use only for rescue with monitoring of heart rate and potassium if needed.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Arformoterol with Terbutaline?

MediHelp rates the interaction as moderate. Arformoterol and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining terbutaline with the long-acting beta-agonist arformoterol duplicates beta-2 stimulation. This raises the chance of tachycardia, arrhythmia, tremor and hypokalemia, particularly in cardiac patients.

How serious is the interaction between Arformoterol and Terbutaline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine use of additional beta-agonists with arformoterol; use only for rescue with monitoring of heart rate and potassium if needed.

What other medicines interact with Terbutaline?

MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.

Full monographs, dosing and an interaction checker in the MediHelp app

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