Drug interactions
Arformoterol + Xylometazoline
Severity: Minor
Arformoterol and Xylometazoline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol is a long-acting beta-2 agonist that can increase heart rate and cause tremor, and xylometazoline is an alpha-agonist decongestant. Additive cardiovascular stimulation is possible, though intranasal xylometazoline is poorly absorbed systemically.
What this interaction means in plain words
Arformoterol and Xylometazoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Arformoterol belongs to Respiratory; Xylometazoline belongs to Respiratory.
Why it happens
Additive sympathomimetic effects through alpha and beta adrenergic stimulation.
What to do
Use xylometazoline briefly at labeled doses and monitor heart rate and blood pressure in patients with heart disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Xylometazoline
- Selegiline + Xylometazoline Contraindicated
- Ergotamine + Xylometazoline Major
- Isocarboxazid + Xylometazoline Major
- Phenelzine + Xylometazoline Major
- Tranylcypromine + Xylometazoline Major
- Amitriptyline + Xylometazoline Moderate
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Xylometazoline?
MediHelp rates the interaction as minor. Arformoterol and Xylometazoline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Arformoterol is a long-acting beta-2 agonist that can increase heart rate and cause tremor, and xylometazoline is an alpha-agonist decongestant. Additive cardiovascular stimulation is possible, though intranasal xylometazoline is poorly absorbed systemically.
How serious is the interaction between Arformoterol and Xylometazoline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use xylometazoline briefly at labeled doses and monitor heart rate and blood pressure in patients with heart disease.
What other medicines interact with Xylometazoline?
MediHelp also lists interactions of Xylometazoline with, for example, Selegiline, Ergotamine, Isocarboxazid. The full list is on the Xylometazoline page.
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