Drug interactions
Artemether / lumefantrine + Formoterol
Severity: Major
Artemether / lumefantrine and Formoterol: major interaction.
Last updated Sources: US FDA label
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can prolong the QT interval, so co-use may raise the risk of torsades de pointes. Lumefantrine labeling warns against combining with other QT-prolonging drugs.
What this interaction means in plain words
Artemether / lumefantrine and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Why it happens
Additive QT prolongation through cardiac repolarization effects.
What to do
Avoid co-use where possible; if unavoidable, check ECG and correct potassium and magnesium before and during treatment.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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References
Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Frequently asked questions
Can I take Artemether / lumefantrine with Formoterol?
MediHelp rates the interaction as major. Artemether / lumefantrine and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both agents can prolong the QT interval, so co-use may raise the risk of torsades de pointes. Lumefantrine labeling warns against combining with other QT-prolonging drugs.
How serious is the interaction between Artemether / lumefantrine and Formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid co-use where possible; if unavoidable, check ECG and correct potassium and magnesium before and during treatment.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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