Drug interactions
Asenapine transdermal + Atomoxetine
Severity: Moderate
Asenapine transdermal and Atomoxetine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Asenapine can prolong the QT interval modestly, and atomoxetine may add to this effect. The risk matters most in patients with cardiac disease, electrolyte disturbance or other QT-prolonging drugs.
What this interaction means in plain words
Asenapine transdermal and Atomoxetine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation.
What to do
Check baseline ECG and electrolytes, and repeat after dose changes. Avoid in patients with known QT prolongation.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Asenapine transdermal with Atomoxetine?
MediHelp rates the interaction as moderate. Asenapine transdermal and Atomoxetine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Asenapine can prolong the QT interval modestly, and atomoxetine may add to this effect. The risk matters most in patients with cardiac disease, electrolyte disturbance or other QT-prolonging drugs.
How serious is the interaction between Asenapine transdermal and Atomoxetine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes, and repeat after dose changes. Avoid in patients with known QT prolongation.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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