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Drug interactions

Acetylsalicylic acid + Cefadroxil

Severity: Minor

Acetylsalicylic acid and Cefadroxil: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Both agents are organic acids eliminated by renal tubular secretion, so they could compete and slightly raise each other's levels. Clinically this is unlikely to matter at usual doses.

What this interaction means in plain words

Acetylsalicylic acid and Cefadroxil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Acetylsalicylic acid belongs to Musculoskeletal; Cefadroxil belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Competition for renal tubular organic anion transport.

What to do

No routine adjustment is needed. Be aware of the possibility in patients with renal impairment on high-dose aspirin.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Acetylsalicylic acid with Cefadroxil?

MediHelp rates the interaction as minor. Acetylsalicylic acid and Cefadroxil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents are organic acids eliminated by renal tubular secretion, so they could compete and slightly raise each other's levels. Clinically this is unlikely to matter at usual doses.

How serious is the interaction between Acetylsalicylic acid and Cefadroxil?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Be aware of the possibility in patients with renal impairment on high-dose aspirin.

What other medicines interact with Acetylsalicylic acid?

MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.

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