Drug interactions
Acetylsalicylic acid + Garlic
Severity: Minor
Acetylsalicylic acid and Garlic: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Garlic supplements have antiplatelet activity and may increase the bleeding tendency when taken with aspirin. Documented clinical bleeding is rare and mostly from case reports.
What this interaction means in plain words
Acetylsalicylic acid and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Acetylsalicylic acid belongs to Musculoskeletal; Garlic belongs to Gastrointestinal Tract.
Why it happens
Garlic constituents such as ajoene inhibit platelet aggregation, which may be additive with aspirin.
What to do
Ask about supplement use and advise reporting unusual bruising or bleeding. Consider stopping garlic supplements before surgery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac intranasal Contraindicated
- Abciximab + Acetylsalicylic acid Major
- Acemetacin + Acetylsalicylic acid Major
- Acetazolamide + Acetylsalicylic acid Major
- Acetylsalicylic acid + Alteplase Major
Other interactions of Garlic
- Garlic + Saquinavir Major
- Aceclofenac + Garlic Moderate
- Acemetacin + Garlic Moderate
- Aescin + Garlic Moderate
- Alteplase + Garlic Moderate
- Argatroban + Garlic Moderate
Frequently asked questions
Can I take Acetylsalicylic acid with Garlic?
MediHelp rates the interaction as minor. Acetylsalicylic acid and Garlic have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Garlic supplements have antiplatelet activity and may increase the bleeding tendency when taken with aspirin. Documented clinical bleeding is rare and mostly from case reports.
How serious is the interaction between Acetylsalicylic acid and Garlic?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about supplement use and advise reporting unusual bruising or bleeding. Consider stopping garlic supplements before surgery.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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