Drug interactions
Aspirin + Ginko biloba
Severity: Moderate
Aspirin and Ginko biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo biloba may inhibit platelet-activating factor, and aspirin irreversibly inhibits platelet aggregation. Case reports describe bleeding with the combination, although controlled studies have not consistently shown increased risk.
What this interaction means in plain words
Aspirin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antiplatelet effects from PAF antagonism by ginkgolides and COX-1 inhibition by aspirin.
What to do
Monitor for bruising, GI and other bleeding, and consider stopping ginkgo if bleeding occurs or before procedures.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Frequently asked questions
Can I take Aspirin with Ginko biloba?
MediHelp rates the interaction as moderate. Aspirin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba may inhibit platelet-activating factor, and aspirin irreversibly inhibits platelet aggregation. Case reports describe bleeding with the combination, although controlled studies have not consistently shown increased risk.
How serious is the interaction between Aspirin and Ginko biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bruising, GI and other bleeding, and consider stopping ginkgo if bleeding occurs or before procedures.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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