Drug interactions
Aspirin rectal + Telmisartan
Severity: Moderate
Aspirin rectal and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rectal aspirin is absorbed systemically and can have the same prostaglandin-related effects as oral aspirin at comparable doses. It may reduce the blood pressure response to telmisartan and impair renal function in vulnerable patients.
What this interaction means in plain words
Aspirin rectal and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Systemic inhibition of renal prostaglandin synthesis reduces renal perfusion and opposes ARB effects.
What to do
Monitor blood pressure, creatinine and potassium if aspirin is used at analgesic doses or for prolonged periods, and keep the patient hydrated.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Aspirin rectal and Telmisartan, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Frequently asked questions
Can I take Aspirin rectal with Telmisartan?
MediHelp rates the interaction as moderate. Aspirin rectal and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Rectal aspirin is absorbed systemically and can have the same prostaglandin-related effects as oral aspirin at comparable doses. It may reduce the blood pressure response to telmisartan and impair renal function in vulnerable patients.
How serious is the interaction between Aspirin rectal and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, creatinine and potassium if aspirin is used at analgesic doses or for prolonged periods, and keep the patient hydrated.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
