Drug interactions
Atenolol + Fenoldopam
Severity: Moderate
Atenolol and Fenoldopam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenoldopam is an intravenous vasodilator for severe hypertension, and atenolol can add to its blood pressure reduction. Beta-blockade may also blunt the reflex tachycardia fenoldopam causes, so hypotension may be less obvious early on.
What this interaction means in plain words
Atenolol and Fenoldopam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic hypotension from dopamine-1 mediated vasodilation and beta-1 blockade.
What to do
Titrate fenoldopam under continuous blood pressure monitoring. Avoid concurrent beta-blockers where possible during infusion, per labeling.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Atenolol and Fenoldopam, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Fenoldopam?
MediHelp rates the interaction as moderate. Atenolol and Fenoldopam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenoldopam is an intravenous vasodilator for severe hypertension, and atenolol can add to its blood pressure reduction. Beta-blockade may also blunt the reflex tachycardia fenoldopam causes, so hypotension may be less obvious early on.
How serious is the interaction between Atenolol and Fenoldopam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate fenoldopam under continuous blood pressure monitoring. Avoid concurrent beta-blockers where possible during infusion, per labeling.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
