Drug interactions
Atenolol + Hydrochlorothiazide-olmesartan
Severity: Minor
Atenolol and Hydrochlorothiazide-olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atenolol and the olmesartan-hydrochlorothiazide combination are often used together and lower blood pressure additively, which can cause hypotension or bradycardia. Beta blockers can slightly raise potassium and thiazides can lower it, and thiazides may also worsen glucose control.
What this interaction means in plain words
Atenolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol belongs to Cardiovascular; Hydrochlorothiazide-olmesartan belongs to Cardiovascular.
Why it happens
Additive antihypertensive pharmacodynamic effects and opposing influences on potassium handling.
What to do
Monitor blood pressure, heart rate and serum potassium when starting or adjusting therapy. Adjust doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Hydrochlorothiazide-olmesartan?
MediHelp rates the interaction as minor. Atenolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atenolol and the olmesartan-hydrochlorothiazide combination are often used together and lower blood pressure additively, which can cause hypotension or bradycardia. Beta blockers can slightly raise potassium and thiazides can lower it, and thiazides may also worsen glucose control.
How serious is the interaction between Atenolol and Hydrochlorothiazide-olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and serum potassium when starting or adjusting therapy. Adjust doses if symptomatic hypotension occurs.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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