Drug interactions
Atenolol + Indacaterol inhaled
Severity: Moderate
Atenolol and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-blockers and beta-2 agonists oppose each other, so atenolol can reduce the bronchodilator effect of indacaterol. Even cardioselective agents can provoke bronchospasm in patients with COPD or asthma, particularly at higher doses.
What this interaction means in plain words
Atenolol and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism at beta-2 receptors, with partial loss of selectivity at higher atenolol doses.
What to do
Use the lowest effective dose of atenolol or another cardioselective agent only when needed, and monitor respiratory symptoms and lung function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Atenolol and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Beta-blockers and beta-2 agonists oppose each other, so atenolol can reduce the bronchodilator effect of indacaterol. Even cardioselective agents can provoke bronchospasm in patients with COPD or asthma, particularly at higher doses.
How serious is the interaction between Atenolol and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective dose of atenolol or another cardioselective agent only when needed, and monitor respiratory symptoms and lung function.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
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