Drug interactions
Atenolol + Indapamide
Severity: Minor
Atenolol and Indapamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indapamide can lower serum potassium while beta-blockers have a small potassium-raising tendency, so the net effect on potassium is unpredictable. The two drugs are often combined for hypertension and additive blood pressure lowering is expected. Indapamide may also modestly worsen glucose and lipid control.
What this interaction means in plain words
Atenolol and Indapamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol belongs to Cardiovascular; Indapamide belongs to Cardiovascular.
Why it happens
Largely additive antihypertensive effect; opposing minor effects on potassium handling, with no clearly established mechanism for the potassium change.
What to do
Monitor blood pressure and electrolytes periodically, especially at initiation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Atenolol and Indapamide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Indapamide
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Indapamide?
MediHelp rates the interaction as minor. Atenolol and Indapamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Indapamide can lower serum potassium while beta-blockers have a small potassium-raising tendency, so the net effect on potassium is unpredictable. The two drugs are often combined for hypertension and additive blood pressure lowering is expected. Indapamide may also modestly worsen glucose and lipid control.
How serious is the interaction between Atenolol and Indapamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and electrolytes periodically, especially at initiation.
What other medicines interact with Indapamide?
MediHelp also lists interactions of Indapamide with, for example, Adagrasib, Amifostine, Amiodarone. The full list is on the Indapamide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
