Drug interactions
Atenolol + Iodixanol
Severity: Moderate
Atenolol and Iodixanol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Patients taking beta-blockers may have more severe hypersensitivity reactions to iodinated contrast. They may also respond poorly to the usual epinephrine treatment.
What this interaction means in plain words
Atenolol and Iodixanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Beta-blockade blunts compensatory sympathetic responses and reduces the response to epinephrine during anaphylactoid reactions.
What to do
Ensure resuscitation equipment is available during contrast administration; glucagon may be used for epinephrine-resistant reactions. Do not stop the beta-blocker routinely.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Iodixanol?
MediHelp rates the interaction as moderate. Atenolol and Iodixanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patients taking beta-blockers may have more severe hypersensitivity reactions to iodinated contrast. They may also respond poorly to the usual epinephrine treatment.
How serious is the interaction between Atenolol and Iodixanol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ensure resuscitation equipment is available during contrast administration; glucagon may be used for epinephrine-resistant reactions. Do not stop the beta-blocker routinely.
What other medicines interact with Atenolol?
MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.
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