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Drug interactions

Atenolol + Sodium citrate / citric acid

Severity: Minor

Atenolol and Sodium citrate / citric acid: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral alkalinizing agents may slightly reduce atenolol absorption. The expected clinical effect is small and rarely noticeable.

What this interaction means in plain words

Atenolol and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible reduction in gastrointestinal absorption of atenolol, with an uncertain mechanism.

What to do

Separate administration by about 2 hours. Monitor heart rate and blood pressure if both are used regularly.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Atenolol with Sodium citrate / citric acid?

MediHelp rates the interaction as minor. Atenolol and Sodium citrate / citric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral alkalinizing agents may slightly reduce atenolol absorption. The expected clinical effect is small and rarely noticeable.

How serious is the interaction between Atenolol and Sodium citrate / citric acid?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate administration by about 2 hours. Monitor heart rate and blood pressure if both are used regularly.

What other medicines interact with Atenolol?

MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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