Drug interactions
Atenolol-chlorthalidone + Glucagon intranasal
Severity: Minor
Atenolol-chlorthalidone and Glucagon intranasal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Glucagon can cause transient rises in pulse and blood pressure, and this may be more pronounced in patients on beta-blockers. Glucagon is sometimes used therapeutically in beta-blocker overdose for its inotropic effects.
What this interaction means in plain words
Atenolol-chlorthalidone and Glucagon intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucagon increases cardiac cAMP independent of beta-receptors and may release catecholamines, producing transient hemodynamic changes.
What to do
Monitor blood pressure and pulse after glucagon administration; no routine dose change is needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atenolol-chlorthalidone
Frequently asked questions
Can I take Atenolol-chlorthalidone with Glucagon intranasal?
MediHelp rates the interaction as minor. Atenolol-chlorthalidone and Glucagon intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Glucagon can cause transient rises in pulse and blood pressure, and this may be more pronounced in patients on beta-blockers. Glucagon is sometimes used therapeutically in beta-blocker overdose for its inotropic effects.
How serious is the interaction between Atenolol-chlorthalidone and Glucagon intranasal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and pulse after glucagon administration; no routine dose change is needed.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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