Drug interactions
Atomoxetine + Buprenorphine buccal
Severity: Moderate
Atomoxetine and Buprenorphine buccal: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Buccal buprenorphine can prolong the QT interval at higher doses. Atomoxetine may add to this effect.
What this interaction means in plain words
Atomoxetine and Buprenorphine buccal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation.
What to do
Obtain a baseline ECG in patients with cardiac risk factors and monitor for palpitations or syncope. Use the lowest effective buprenorphine dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Buprenorphine buccal?
MediHelp rates the interaction as moderate. Atomoxetine and Buprenorphine buccal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Buccal buprenorphine can prolong the QT interval at higher doses. Atomoxetine may add to this effect.
How serious is the interaction between Atomoxetine and Buprenorphine buccal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG in patients with cardiac risk factors and monitor for palpitations or syncope. Use the lowest effective buprenorphine dose.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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