Drug interactions
Atomoxetine + Buprenorphine subdermal implant
Severity: Moderate
Atomoxetine and Buprenorphine subdermal implant: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Buprenorphine has a small QT-prolonging effect, and atomoxetine could add to it. The implant gives low, steady exposure, so the effect is probably modest.
What this interaction means in plain words
Atomoxetine and Buprenorphine subdermal implant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation.
What to do
Review other QT-prolonging drugs and electrolytes, and obtain an ECG in patients with cardiac risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Buprenorphine subdermal implant?
MediHelp rates the interaction as moderate. Atomoxetine and Buprenorphine subdermal implant can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Buprenorphine has a small QT-prolonging effect, and atomoxetine could add to it. The implant gives low, steady exposure, so the effect is probably modest.
How serious is the interaction between Atomoxetine and Buprenorphine subdermal implant?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review other QT-prolonging drugs and electrolytes, and obtain an ECG in patients with cardiac risk factors.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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