Drug interactions
Atomoxetine + Buprenorphine transdermal
Severity: Moderate
Atomoxetine and Buprenorphine transdermal: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Transdermal buprenorphine can prolong the QT interval, particularly at higher patch strengths. Atomoxetine may increase this risk.
What this interaction means in plain words
Atomoxetine and Buprenorphine transdermal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT prolongation.
What to do
Use the lowest effective patch strength and monitor ECG in patients with cardiac risk factors or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Buprenorphine transdermal?
MediHelp rates the interaction as moderate. Atomoxetine and Buprenorphine transdermal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Transdermal buprenorphine can prolong the QT interval, particularly at higher patch strengths. Atomoxetine may increase this risk.
How serious is the interaction between Atomoxetine and Buprenorphine transdermal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest effective patch strength and monitor ECG in patients with cardiac risk factors or other QT-prolonging drugs.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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