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Drug interactions

Atomoxetine + Indacaterol inhaled

Severity: Moderate

Atomoxetine and Indacaterol inhaled: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Indacaterol is a long-acting beta-agonist that can cause tachycardia and QT prolongation, and atomoxetine also raises heart rate and blood pressure. Together they may add to cardiovascular stimulation and arrhythmia risk, though inhaled exposure is low.

What this interaction means in plain words

Atomoxetine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive adrenergic cardiovascular effects and possible QTc prolongation.

What to do

Monitor heart rate, blood pressure and palpitations, and obtain an ECG if symptoms or other risk factors are present. Use the lowest effective doses.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Atomoxetine with Indacaterol inhaled?

MediHelp rates the interaction as moderate. Atomoxetine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol is a long-acting beta-agonist that can cause tachycardia and QT prolongation, and atomoxetine also raises heart rate and blood pressure. Together they may add to cardiovascular stimulation and arrhythmia risk, though inhaled exposure is low.

How serious is the interaction between Atomoxetine and Indacaterol inhaled?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and palpitations, and obtain an ECG if symptoms or other risk factors are present. Use the lowest effective doses.

What other medicines interact with Atomoxetine?

MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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