Drug interactions
Atomoxetine + Inotuzumab
Severity: Moderate
Atomoxetine and Inotuzumab: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inotuzumab ozogamicin is labeled to prolong the QT interval, and atomoxetine may add a small additional effect. This could increase the risk of arrhythmia in a patient who is already vulnerable.
What this interaction means in plain words
Atomoxetine and Inotuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Monitor ECG and electrolytes at baseline and during inotuzumab treatment. Correct electrolyte abnormalities and consider holding atomoxetine if QTc rises significantly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Inotuzumab?
MediHelp rates the interaction as moderate. Atomoxetine and Inotuzumab can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inotuzumab ozogamicin is labeled to prolong the QT interval, and atomoxetine may add a small additional effect. This could increase the risk of arrhythmia in a patient who is already vulnerable.
How serious is the interaction between Atomoxetine and Inotuzumab?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes at baseline and during inotuzumab treatment. Correct electrolyte abnormalities and consider holding atomoxetine if QTc rises significantly.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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