Drug interactions
Atomoxetine + Metaproterenol
Severity: Moderate
Atomoxetine and Metaproterenol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atomoxetine may potentiate the cardiovascular effects of beta-agonists such as metaproterenol, including tachycardia and hypertension. Systemic use carries more risk than inhaled use.
What this interaction means in plain words
Atomoxetine and Metaproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive sympathomimetic effects on heart rate and blood pressure.
What to do
Monitor heart rate and blood pressure, especially with oral metaproterenol or high doses. Reduce the beta-agonist dose if cardiovascular effects appear.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Metaproterenol?
MediHelp rates the interaction as moderate. Atomoxetine and Metaproterenol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atomoxetine may potentiate the cardiovascular effects of beta-agonists such as metaproterenol, including tachycardia and hypertension. Systemic use carries more risk than inhaled use.
How serious is the interaction between Atomoxetine and Metaproterenol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure, especially with oral metaproterenol or high doses. Reduce the beta-agonist dose if cardiovascular effects appear.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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