Drug interactions
Atomoxetine + Octreotide
Severity: Moderate
Atomoxetine and Octreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Octreotide can cause bradycardia and conduction abnormalities including QT prolongation. Atomoxetine may add to the effect on repolarization in patients with other risk factors.
What this interaction means in plain words
Atomoxetine and Octreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Octreotide belongs to Endocrine.
Why it happens
Additive effects on cardiac conduction and repolarization.
What to do
Obtain a baseline ECG and monitor heart rate and rhythm in patients with cardiac disease. Keep electrolytes within normal limits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Other interactions of Octreotide
Frequently asked questions
Can I take Atomoxetine with Octreotide?
MediHelp rates the interaction as moderate. Atomoxetine and Octreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Octreotide can cause bradycardia and conduction abnormalities including QT prolongation. Atomoxetine may add to the effect on repolarization in patients with other risk factors.
How serious is the interaction between Atomoxetine and Octreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor heart rate and rhythm in patients with cardiac disease. Keep electrolytes within normal limits.
What other medicines interact with Atomoxetine?
MediHelp also lists interactions of Atomoxetine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Atomoxetine page.
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