Drug interactions
Atomoxetine + Terbutaline
Severity: Moderate
Atomoxetine and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atomoxetine raises noradrenergic tone and can increase heart rate and blood pressure, and systemic beta-2 agonists such as terbutaline can add to these effects. The risk is greater with oral or injected terbutaline than with inhaled beta-agonists.
What this interaction means in plain words
Atomoxetine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Terbutaline belongs to Respiratory.
Why it happens
Additive adrenergic effects from norepinephrine reuptake inhibition and beta-receptor stimulation.
What to do
Monitor heart rate and blood pressure when systemic terbutaline is used with atomoxetine. Reduce the dose of either drug if significant tachycardia or hypertension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Terbutaline?
MediHelp rates the interaction as moderate. Atomoxetine and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atomoxetine raises noradrenergic tone and can increase heart rate and blood pressure, and systemic beta-2 agonists such as terbutaline can add to these effects. The risk is greater with oral or injected terbutaline than with inhaled beta-agonists.
How serious is the interaction between Atomoxetine and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when systemic terbutaline is used with atomoxetine. Reduce the dose of either drug if significant tachycardia or hypertension develops.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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