Drug interactions
Azficel-t + Fenoprofen
Severity: Moderate
Azficel-t and Fenoprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is injected intradermally after skin biopsy, and NSAIDs can increase bruising and bleeding at the biopsy and injection sites. Labeling advises against NSAID use around these procedures.
What this interaction means in plain words
Azficel-t and Fenoprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
NSAID-induced reversible platelet COX-1 inhibition impairs hemostasis at procedure sites.
What to do
Stop fenoprofen before the biopsy and injection sessions for a suitable period, as advised in the product labeling. Use paracetamol for analgesia and inspect the sites for bleeding.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fenoprofen
- Fenoprofen + Ketorolac Contraindicated
- Fenoprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Fenoprofen Major
- Acemetacin + Fenoprofen Major
- Acetylsalicylic acid + Fenoprofen Major
- Alteplase + Fenoprofen Major
Frequently asked questions
Can I take Azficel-t with Fenoprofen?
MediHelp rates the interaction as moderate. Azficel-t and Fenoprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is injected intradermally after skin biopsy, and NSAIDs can increase bruising and bleeding at the biopsy and injection sites. Labeling advises against NSAID use around these procedures.
How serious is the interaction between Azficel-t and Fenoprofen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop fenoprofen before the biopsy and injection sessions for a suitable period, as advised in the product labeling. Use paracetamol for analgesia and inspect the sites for bleeding.
What other medicines interact with Fenoprofen?
MediHelp also lists interactions of Fenoprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Fenoprofen page.
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