Drug interactions
Azficel-t + Ketorolac
Severity: Moderate
Azficel-t and Ketorolac: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is given by intradermal injection after a skin biopsy, and NSAIDs may increase bruising and bleeding at the biopsy and injection sites. Ketorolac is a strong inhibitor of platelet aggregation, so this effect may be pronounced.
What this interaction means in plain words
Azficel-t and Ketorolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Ketorolac inhibits platelet cyclooxygenase, impairing platelet aggregation and increasing local bleeding and bruising.
What to do
Avoid ketorolac and other NSAIDs around the time of biopsy and injection sessions, as advised by the product labeling. Use a non-NSAID analgesic such as paracetamol if needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Frequently asked questions
Can I take Azficel-t with Ketorolac?
MediHelp rates the interaction as moderate. Azficel-t and Ketorolac can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is given by intradermal injection after a skin biopsy, and NSAIDs may increase bruising and bleeding at the biopsy and injection sites. Ketorolac is a strong inhibitor of platelet aggregation, so this effect may be pronounced.
How serious is the interaction between Azficel-t and Ketorolac?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac and other NSAIDs around the time of biopsy and injection sessions, as advised by the product labeling. Use a non-NSAID analgesic such as paracetamol if needed.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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