Drug interactions
Basiliximab + Measles vaccine
Severity: Contraindicated
Basiliximab and Measles vaccine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Measles vaccine is live attenuated and can cause disseminated vaccine-strain disease in immunosuppressed patients. Basiliximab also reduces the likelihood of an effective response.
What this interaction means in plain words
Basiliximab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
IL-2 receptor blockade impairs T-cell control of live attenuated virus replication.
What to do
Do not give live measles vaccine during basiliximab therapy; vaccinate before transplant and consider immune globulin after exposure.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Basiliximab
- Basiliximab + Bcg vaccine live Contraindicated
- Basiliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Basiliximab + Measles mumps and rubella vaccine Contraindicated
- Basiliximab + Measles mumps and rubella vaccine live Contraindicated
- Basiliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Basiliximab + Rotavirus oral vaccine live Contraindicated
Frequently asked questions
Can I take Basiliximab with Measles vaccine?
MediHelp rates the interaction as contraindicated. Basiliximab and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated and can cause disseminated vaccine-strain disease in immunosuppressed patients. Basiliximab also reduces the likelihood of an effective response.
How serious is the interaction between Basiliximab and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live measles vaccine during basiliximab therapy; vaccinate before transplant and consider immune globulin after exposure.
What other medicines interact with Basiliximab?
MediHelp also lists interactions of Basiliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Basiliximab page.
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