Drug interactions
Bendroflumethiazide + Formoterol
Severity: Moderate
Bendroflumethiazide and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can lower serum potassium, and together they may cause significant hypokalemia with a risk of arrhythmia, especially in patients with heart disease or on digoxin.
What this interaction means in plain words
Bendroflumethiazide and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Beta-2 agonism shifts potassium into cells while the thiazide increases renal potassium loss.
What to do
Monitor serum potassium and magnesium and replace as needed, particularly with high formoterol doses or in acute asthma.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Frequently asked questions
Can I take Bendroflumethiazide with Formoterol?
MediHelp rates the interaction as moderate. Bendroflumethiazide and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can lower serum potassium, and together they may cause significant hypokalemia with a risk of arrhythmia, especially in patients with heart disease or on digoxin.
How serious is the interaction between Bendroflumethiazide and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium and replace as needed, particularly with high formoterol doses or in acute asthma.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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