Drug interactions
Bendroflumethiazide + Propranolol
Severity: Minor
Bendroflumethiazide and Propranolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Thiazides and beta-blockers are often used together for hypertension and the combination is generally effective. Thiazides can cause hypokalemia and hyperglycemia, and propranolol may mask hypoglycemia and add to metabolic effects.
What this interaction means in plain words
Bendroflumethiazide and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive antihypertensive effects; thiazide-induced potassium loss and glucose intolerance combine with beta-blocker metabolic effects.
What to do
Monitor blood pressure, serum potassium and glucose periodically, particularly in diabetic patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Propranolol
- Propranolol + Thioridazine Contraindicated
- Acebutolol + Propranolol Major
- Adrenaline-articaine + Propranolol Major
- Albuterol + Propranolol Major
- Amifostine + Propranolol Major
- Amiodarone + Propranolol Major
Frequently asked questions
Can I take Bendroflumethiazide with Propranolol?
MediHelp rates the interaction as minor. Bendroflumethiazide and Propranolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Thiazides and beta-blockers are often used together for hypertension and the combination is generally effective. Thiazides can cause hypokalemia and hyperglycemia, and propranolol may mask hypoglycemia and add to metabolic effects.
How serious is the interaction between Bendroflumethiazide and Propranolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, serum potassium and glucose periodically, particularly in diabetic patients.
What other medicines interact with Propranolol?
MediHelp also lists interactions of Propranolol with, for example, Thioridazine, Acebutolol, Adrenaline-articaine. The full list is on the Propranolol page.
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