Drug interactions
Bendroflumethiazide + Telmisartan-amlodipine
Severity: Moderate
Bendroflumethiazide and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both telmisartan and a thiazide diuretic lower blood pressure, and the combination is commonly used. Excess volume depletion, hypotension and electrolyte disturbance can occur, though telmisartan partly offsets thiazide-induced hypokalemia.
What this interaction means in plain words
Bendroflumethiazide and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive antihypertensive and volume-depleting effects, with opposing effects on potassium.
What to do
Monitor blood pressure, renal function, sodium and potassium after starting or changing doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Bendroflumethiazide and Telmisartan-amlodipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Frequently asked questions
Can I take Bendroflumethiazide with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Bendroflumethiazide and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both telmisartan and a thiazide diuretic lower blood pressure, and the combination is commonly used. Excess volume depletion, hypotension and electrolyte disturbance can occur, though telmisartan partly offsets thiazide-induced hypokalemia.
How serious is the interaction between Bendroflumethiazide and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, renal function, sodium and potassium after starting or changing doses.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
