Drug interactions
Bendroflumethiazide + Terbutaline
Severity: Moderate
Bendroflumethiazide and Terbutaline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Terbutaline and thiazide diuretics can each lower serum potassium. Together hypokalemia may be more pronounced and can promote arrhythmias, especially with high-dose or nebulized terbutaline.
What this interaction means in plain words
Bendroflumethiazide and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypokalemia from beta-2 mediated cellular potassium uptake and thiazide renal potassium loss.
What to do
Monitor serum potassium and magnesium, particularly when terbutaline is given in high doses, and replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terbutaline
Frequently asked questions
Can I take Bendroflumethiazide with Terbutaline?
MediHelp rates the interaction as moderate. Bendroflumethiazide and Terbutaline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Terbutaline and thiazide diuretics can each lower serum potassium. Together hypokalemia may be more pronounced and can promote arrhythmias, especially with high-dose or nebulized terbutaline.
How serious is the interaction between Bendroflumethiazide and Terbutaline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium, particularly when terbutaline is given in high doses, and replace potassium as needed.
What other medicines interact with Terbutaline?
MediHelp also lists interactions of Terbutaline with, for example, Carvedilol, Droperidol, Fexinidazole. The full list is on the Terbutaline page.
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