Drug interactions
Benzphetamine + Butorphanol
Severity: Minor
Benzphetamine and Butorphanol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benzphetamine is a sympathomimetic anorectic that may partly oppose sedation, but no reliable clinical interaction is established. Cardiovascular stimulation and sedation effects are unpredictable.
What this interaction means in plain words
Benzphetamine and Butorphanol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible opposing CNS effects; mechanism not well established.
What to do
No dose adjustment is required; do not use benzphetamine to offset opioid sedation. Monitor heart rate and blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Benzphetamine and Butorphanol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Butorphanol
- Butorphanol + Olanzapine / samidorphan Contraindicated
- Butorphanol + Sodium oxybate Contraindicated
- Alfentanil + Butorphanol Major
- Alprazolam + Butorphanol Major
- Alvimopan + Butorphanol Major
- Amobarbital + Butorphanol Major
Frequently asked questions
Can I take Benzphetamine with Butorphanol?
MediHelp rates the interaction as minor. Benzphetamine and Butorphanol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Benzphetamine is a sympathomimetic anorectic that may partly oppose sedation, but no reliable clinical interaction is established. Cardiovascular stimulation and sedation effects are unpredictable.
How serious is the interaction between Benzphetamine and Butorphanol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required; do not use benzphetamine to offset opioid sedation. Monitor heart rate and blood pressure.
What other medicines interact with Butorphanol?
MediHelp also lists interactions of Butorphanol with, for example, Olanzapine / samidorphan, Sodium oxybate, Alfentanil. The full list is on the Butorphanol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
