Drug interactions
Benzphetamine + Diltiazem
Severity: Moderate
Benzphetamine and Diltiazem: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Benzphetamine is a sympathomimetic anorectic that can raise blood pressure and heart rate, opposing the antihypertensive and rate-controlling effects of diltiazem.
What this interaction means in plain words
Benzphetamine and Diltiazem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Pharmacodynamic antagonism through sympathomimetic stimulation.
What to do
Monitor blood pressure and heart rate, and adjust antihypertensive therapy or stop benzphetamine if control is lost.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Diltiazem
- Diltiazem + Flibanserin Contraindicated
- Diltiazem + Ivabradine Contraindicated
- Diltiazem + Lomitapide Contraindicated
- Diltiazem + Lonafarnib Contraindicated
- Acebutolol + Diltiazem Major
- Alfentanil + Diltiazem Major
Frequently asked questions
Can I take Benzphetamine with Diltiazem?
MediHelp rates the interaction as moderate. Benzphetamine and Diltiazem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Benzphetamine is a sympathomimetic anorectic that can raise blood pressure and heart rate, opposing the antihypertensive and rate-controlling effects of diltiazem.
How serious is the interaction between Benzphetamine and Diltiazem?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and adjust antihypertensive therapy or stop benzphetamine if control is lost.
What other medicines interact with Diltiazem?
MediHelp also lists interactions of Diltiazem with, for example, Flibanserin, Ivabradine, Lomitapide. The full list is on the Diltiazem page.
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