Skip to content

Drug interactions

Betaxolol + Butalbital

Severity: Minor

Betaxolol and Butalbital: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Butalbital is a barbiturate that may induce hepatic enzymes and lower betaxolol exposure. Beta-blocker efficacy may be reduced, particularly with regular use.

What this interaction means in plain words

Betaxolol and Butalbital have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Barbiturate-mediated hepatic enzyme induction may increase betaxolol metabolism.

What to do

Monitor blood pressure and heart rate if butalbital is used regularly, and adjust the betaxolol dose if control is lost.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Betaxolol and Butalbital, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Betaxolol with Butalbital?

MediHelp rates the interaction as minor. Betaxolol and Butalbital have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Butalbital is a barbiturate that may induce hepatic enzymes and lower betaxolol exposure. Beta-blocker efficacy may be reduced, particularly with regular use.

How serious is the interaction between Betaxolol and Butalbital?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate if butalbital is used regularly, and adjust the betaxolol dose if control is lost.

What other medicines interact with Betaxolol?

MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in