Drug interactions
Betaxolol + Fenoldopam
Severity: Moderate
Betaxolol and Fenoldopam: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenoldopam is an intravenous dopamine D1 agonist that lowers blood pressure. Beta blockers can add to the hypotensive effect and may blunt the reflex tachycardia that normally accompanies fenoldopam. Fenoldopam labeling advises avoiding beta blockers because of the risk of unexpected hypotension.
What this interaction means in plain words
Betaxolol and Fenoldopam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hypotension from D1-mediated vasodilation and beta blockade, with blunted reflex tachycardia.
What to do
Monitor blood pressure and heart rate continuously during fenoldopam infusion and titrate the dose carefully. Consider holding betaxolol during the infusion if hypotension occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Fenoldopam?
MediHelp rates the interaction as moderate. Betaxolol and Fenoldopam can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenoldopam is an intravenous dopamine D1 agonist that lowers blood pressure. Beta blockers can add to the hypotensive effect and may blunt the reflex tachycardia that normally accompanies fenoldopam. Fenoldopam labeling advises avoiding beta blockers because of the risk of unexpected hypotension.
How serious is the interaction between Betaxolol and Fenoldopam?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate continuously during fenoldopam infusion and titrate the dose carefully. Consider holding betaxolol during the infusion if hypotension occurs.
What other medicines interact with Betaxolol?
MediHelp also lists interactions of Betaxolol with, for example, Acebutolol, Aldesleukin, Amifostine. The full list is on the Betaxolol page.
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