Drug interactions
Betaxolol + Hydrochlorothiazide-olmesartan
Severity: Minor
Betaxolol and Hydrochlorothiazide-olmesartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Betaxolol adds to the antihypertensive effect of olmesartan and hydrochlorothiazide, which is often intended but may cause hypotension or bradycardia. Potassium shifts are modest, and thiazides may impair glucose tolerance and mask some hypoglycemia symptoms with beta blockers.
What this interaction means in plain words
Betaxolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Hydrochlorothiazide-olmesartan belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering through beta-adrenergic blockade, RAAS blockade and diuresis.
What to do
Monitor blood pressure and heart rate when combining or adjusting doses. Check potassium periodically.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-olmesartan
- Aliskiren + Hydrochlorothiazide-olmesartan Contraindicated
- Dofetilide + Hydrochlorothiazide-olmesartan Contraindicated
- Hydrochlorothiazide-olmesartan + Sparsentan Contraindicated
- Acemetacin + Hydrochlorothiazide-olmesartan Major
- Amifostine + Hydrochlorothiazide-olmesartan Major
- Amiloride + Hydrochlorothiazide-olmesartan Major
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Hydrochlorothiazide-olmesartan?
MediHelp rates the interaction as minor. Betaxolol and Hydrochlorothiazide-olmesartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Betaxolol adds to the antihypertensive effect of olmesartan and hydrochlorothiazide, which is often intended but may cause hypotension or bradycardia. Potassium shifts are modest, and thiazides may impair glucose tolerance and mask some hypoglycemia symptoms with beta blockers.
How serious is the interaction between Betaxolol and Hydrochlorothiazide-olmesartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when combining or adjusting doses. Check potassium periodically.
What other medicines interact with Hydrochlorothiazide-olmesartan?
MediHelp also lists interactions of Hydrochlorothiazide-olmesartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-olmesartan page.
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