Drug interactions
Betaxolol + Ketorolac
Severity: Minor
Betaxolol and Ketorolac: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ketorolac may reduce the antihypertensive effect of betaxolol, mainly when used for more than a few days. The effect is usually modest and variable.
What this interaction means in plain words
Betaxolol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Betaxolol belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
Why it happens
NSAIDs inhibit vasodilatory prostaglandin synthesis and promote sodium and fluid retention, opposing the blood pressure lowering of beta-blockers.
What to do
Monitor blood pressure if ketorolac is continued beyond a few days. Adjust the antihypertensive regimen if control is lost.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Betaxolol
- Acebutolol + Betaxolol Major
- Aldesleukin + Betaxolol Major
- Amifostine + Betaxolol Major
- Amiodarone + Betaxolol Major
- Atenolol-chlorthalidone + Betaxolol Major
- Atenolol + Betaxolol Major
Frequently asked questions
Can I take Betaxolol with Ketorolac?
MediHelp rates the interaction as minor. Betaxolol and Ketorolac have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ketorolac may reduce the antihypertensive effect of betaxolol, mainly when used for more than a few days. The effect is usually modest and variable.
How serious is the interaction between Betaxolol and Ketorolac?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure if ketorolac is continued beyond a few days. Adjust the antihypertensive regimen if control is lost.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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